DNA backbone is the key structural component of the double-helix DNA molecule. The backbone of DNA is made up of sugar and phosphate molecules that form a chain that runs along the length of the DNA strand. Some synonyms for the DNA backbone include the sugar-phosphate backbone, the phosphate-sugar backbone, and the deoxyribose-phosphate backbone. These all refer to the same structure but arrange the descriptive terms in a slightly different order. Other terms that may be used to describe the DNA backbone include the DNA chain, the DNA strand backbone, or the DNA backbone structure. Regardless of the terminology used, the importance of the DNA backbone cannot be understated as it provides the support and stability necessary for proper DNA replication and transmission of genetic information.