The most common synonyms for the phrase "do with" are "deal with" and "handle." Both of these phrases suggest taking control of a situation or task, whether it be to manage or accomplish it. Other synonyms include "interact with," "treat," or "work with." These phrases all convey a sense of action, with the subject being involved in the situation at hand. Other phrases, such as "have to do with" or "relate to," suggest a connection or relevance between two things. However, the overall meaning is similar, with the subject taking an active role in the matter in question.