"Make the most of" is a commonly used phrase in English that means to take full advantage of a situation or opportunity. However, there are many other synonyms that can be used to express the same sentiment, such as "seize the day," "capitalize on," "exploit," "utilize," "maximize," "optimize," "benefit from," "leverage," "milk," and "turn to one's advantage." Each of these synonyms can be used in a slightly different context depending on the specific situation, but they all convey the idea of making the most of an opportunity that presents itself.