"Drive round the bend" is a common phrase used to describe a situation where someone or something is irritating or frustrating to the point of causing anger or madness. There are many synonyms that can be used in place of this phrase, including "drive up the wall," "drive someone crazy," "drive nuts," "drive insane," and "drive bonkers." These phrases convey the same meaning and can be used interchangeably based on the context. The phrase is often used in a light-hearted manner to describe everyday annoyances, but it can also be used to express serious frustration or anger towards a situation or person.