"Drive someone round the bend" is a colloquial expression used to signify a strong sense of annoyance caused by someone's behavior or situation. However, if you're tired of repeating the same phrase and want to add some spice to your conversations, you can use synonyms such as "drive someone up the wall," "drive someone crazy," "drive someone insane," "get under someone's skin," "exasperate someone," or "put someone on edge." These phrases capture the same essence of frustration expressed in different words. Switching up the words will keep your communication fresh, interesting, and impactful, ultimately leading to a better understanding of the situation.