There are several synonyms for the phrase "end in disappointment," depending on the context of the situation. Some synonyms include "result in frustration or failure," "conclude in letdown," "finish in dissatisfaction," "terminate in discontent," or "culminate in despair." These phrases all describe a scenario where one's hopes or expectations are not met, and the end result is a feeling of dissatisfaction or disillusionment. It is important to note that while disappointment may feel discouraging, it can often be used as a learning experience to try again and approach situations differently in the future.