Enkephalin is an endogenous opioid peptide that acts as a natural painkiller. It is a neurotransmitter that interacts with receptors in the brain to help regulate pain. Although "enkephalin" is the most commonly used term for this peptide, it has several synonyms. Some of the more common synonyms include "leucine-enkephalin," "met-enkephalin," and "Tyr-Gly-Gly-Phe-Leu." These synonyms all refer to the same group of peptides and are often used interchangeably in scientific literature. Enkephalins have been studied for their potential in pain management, addiction treatment, and mood regulation. As research continues to uncover new aspects of this peptide's function, more synonyms may emerge in the future.