Eupatorium Perfoliatum, commonly referred to as "Boneset," is a medicinal plant that has been used for various purposes for centuries. It is celebrated for its ability to treat fevers, colds, and other respiratory-related ailments. Boneset shares similarities with other plants such as snakeroot, teasel, and ague-weed, which are known for their potential to heal a range of diseases. Other plants that closely resemble Boneset include Indian sage, Joe-Pye weed, and thoroughwort. Despite the various synonyms available, Eupatorium Perfoliatum remains a popular medicinal plant that has benefitted many people over the years.