"Fill with loathing" is a phrase that denotes a strong emotional response towards someone or something. Antonyms of this phrase would be words that indicate a positive, neutral or weak emotional response. The antonyms for "fill with loathing" could be words such as adore, cherish, appreciate, respect, like, admire, appreciate, delight, enjoy, and fondness. These words signify a feeling of positive acceptance or indifference towards the subject, which is the opposite of loathing. Using these words in place of the negative phrase "fill with loathing" can help convey a more optimistic and welcoming tone, and help facilitate mutual understanding and agreement.