Despise is a strong word that conveys an extreme level of dislike or hatred towards someone or something. Synonyms for the word despise include detest, loathe, abhor, hate, revile, scorn, and repudiate. These words express an intense feeling of dislike for something that is considered highly objectionable or offensive. Other synonyms for despise include disdain, contempt, and disregard, which imply a strong feeling of disrespect towards someone or something. These words can be used to describe emotions felt towards a person, an idea, or an object. All of these synonyms emphasize strong negative emotions and the rejection of something or someone.