Antonyms for the phrase "wast down and out" include a range of positive terms that suggest thriving and success, such as "prosperous," "flourishing," "thriving," "successful," "victorious," "triumphant," and "accomplished." Other antonyms for this phrase could include words that suggest strength and resilience, such as "resilient," "determined," "persistent," "unyielding," and "unwavering." Ultimately, the antonyms for "wast down and out" all suggest a positive and optimistic outlook, one that emphasizes the ability to overcome adversity and achieve success no matter what challenges may arise along the way.