Antonyms for "sets one's heart on" include letting go, releasing, detaching, and relinquishing. These terms imply the act of consciously and intentionally freeing oneself from the attachment or desire for a particular person, thing, or outcome. While setting one's heart on something can be a driving force for passion and ambition, it can also lead to disappointment and distress when the desired outcome is not achieved. Letting go and detaching can bring a sense of freedom, mindfulness, and acceptance of the present moment, allowing for greater clarity and inner peace.
