Antonyms for "set store by" could include words such as disregard, ignore, neglect, or overlook. These words suggest a lack of importance or value placed on a particular idea or item. When someone does not set store by something, they are not prioritizing it or making it a priority in their lives. This could apply to beliefs, relationships, possessions, or opinions. Antonyms for "set store by" are useful in demonstrating a lack of interest or a difference in priorities, and can help to clarify or emphasize the speaker's point of view.