The phrase "are in need of" can be substituted with various synonyms depending on the context. A few commonly used options include "need," "require," "demand," "crave," "desire," "yearn for," "long for," "seek," "want," and "have need of." Each of these synonyms conveys a slightly different tone or emphasis, so it's important to consider the specific nuances of the situation in which the phrase is being used. For example, "require" suggests a more urgent or necessary need, while "yearn for" implies a deep desire or longing. Ultimately, choosing the best synonym for "are in need of" involves considering the overall tone and context of the message being conveyed.