The "genotype-first approach" refers to a method of patient diagnosis and treatment based on their genetic makeup. Synonyms for this term include "genetics-driven approach," "precision medicine," and "personalized medicine." This approach involves analyzing a patient's genes to identify potential health risks, personalized treatment options, and drug therapy responses. By taking this approach, physicians can provide tailored treatment that is specific to the individual's genetic makeup. Other synonyms include "individualized medicine," "molecular medicine," and "pharmacogenomics." The genotype-first approach is becoming increasingly popular with the growing availability of genetic testing, which is making personalized medicine more accessible to patients.