Antonyms for the phrase "go toe to toe with" could include "avoid confrontation," "back down," "surrender," or "give in." These words indicate a lack of willingness to engage in a competitive, confrontational or challenging situation. Instead of facing difficulties head-on, one may choose to turn the other cheek, run away, or accept defeat without a fight. While this may be a strategy to avoid conflict or injury, it may also indicate a lack of courage, conviction or determination to stand up for oneself or one's beliefs. In contrast, synonyms for "go toe to toe with" may include "compete," "engage," "battle," "challenge," or "confront.