When we want to express the idea of opposing something or acting in contradiction to it, there are various synonyms for the expression "go against" that we can use. Some of the most common ones include "contradict," "dispute," "defy," "resist," "oppose," "rebel," "counter," "challenge," "opposite," and "thwart." Each of these words has its own particular nuance and context in which it is most appropriate. For example, "contradict" may be the best choice for a situation where one statement directly contradicts another, while "defy" might be more suitable for a more dramatic act of rebellion or resistance. Regardless of which synonym we choose, they are all powerful ways to express the idea of going against something.