"Come up against" is a verb phrase used to describe facing an obstacle or challenge. Synonyms for this phrase are abundant and can help to vary your language use. Some alternatives may include "encounter," "confront," "face," "meet," or "confront." Each of these words can add a unique nuance to your writing or speech. For example, "encounter" suggests that the obstacle was unexpected, while "confront" implies facing something head-on, with intent. Using synonyms for "come up against" can not only enhance your communication skills but also make your writing more interesting and engaging.