The Hardy-Weinberg principle, also known as the Hardy-Weinberg equilibrium, is a fundamental concept in population genetics. It states that the frequency of alleles in a population will not change over time if certain conditions are met, including random mating, no migration, no genetic drift, no mutation, and no natural selection. Synonyms for this principle include the law of genetic equilibrium, the law of αβ equilibrium, and the principle of genetic constancy. The Hardy-Weinberg principle provides a baseline understanding of population genetics and is widely used in research studies to estimate allele frequencies, test for genetic disequilibrium, and develop hypotheses about population dynamics.