The antonyms for the term "heart's desires" can refer to things that one absolutely does not desire or ones that are contrary to their wishes. These could include words like hates, loathes, disgusts, detests, repels, or despises. These opposites suggest a deep-seated aversion or revulsion toward whatever it is that is being described. Alternatively, antonyms of "heart's desires" could refer to things that are not desired, simply because they don't interest the person or because they are indifferent to them. Such antonyms may include words like disinterested, bored, apathetic, uninterested, or uncaring.
Overall, the antonyms for "heart's desires" paint a picture of negativity, indifference, or outright opposition to the things that one truly desires in life.