The phrase "highly strung" is often used to describe someone who is easily agitated or nervous. Synonyms for this phrase include "high-strung," "edgy," "anxious," "jittery," "tense," "nervous," and "wound up." Other similar terms include "fidgety," "restless," "jumpy," "overwrought," "neurotic," and "stressed out." These adjectives all describe someone who is emotionally charged, perhaps due to stress, anxiety, or pressure. While some of these words may have a slightly negative connotation, they all accurately describe someone who is feeling frazzled or on edge. If you are feeling highly strung yourself, try to take a break, relax, and regroup.