The phrase "hold out against" refers to resisting or enduring something, usually a challenge or opposition. Some synonyms for this phrase include "withstand," "oppose," "defy," "resist," "keep at bay," "stand firm," and "hold the line." These words indicate the power of one's will to keep fighting and not give up, even when faced with daunting obstacles. Other related terms include "persevere," "persist," "endure," "tough it out," and "hang in there." These synonyms demonstrate the determination and stubbornness necessary to overcome adversity and emerge victorious. When faced with tough times, it is important to remember these words and to hold out against whatever is in our way.