The phrase "holds out against" is often used to describe someone or something resisting or opposing a particular action or situation. The antonyms or opposite words for this phrase may include terms such as surrender, yield, give in, acquiesce, submit, or comply. These words suggest a willingness to accept or adapt to a change or circumstance rather than fighting against it. Other antonyms might include accept, embrace, welcome, approve, support, or champion, which signify an active affirmation or endorsement of a particular course of action or outcome. Antonyms for "holds out against" indicate a different approach to dealing with difficulties or challenges.