Homeobox genes are essential genes that play a crucial role in the embryonic development of all animals. They work by encoding for a sequence of proteins called transcription factors, which bind to specific DNA sites and are responsible for turning genes on and off. Synonyms for homeobox gene include Hox genes, HOX transcription factors, or developmental genes. These genes are highly conserved throughout evolution and are present in all animals, from insects to humans. They are responsible for the basic body plan of all animals and determine the identity and position of body segments along the anterior-posterior axis. Understanding the function and regulation of homeobox genes is important in the study of animal development and the evolution of biodiversity.