Hydroflumethiazide is a medication used to treat high blood pressure and edema. While it is a specific drug, there are other medications that have similar properties and are sometimes used interchangeably. Some synonyms for hydroflumethiazide are hydrochlorothiazide, chlorthalidone, indapamide, and metolazone. Hydrochlorothiazide is another diuretic medication that is often used instead of hydroflumethiazide, while chlorthalidone is a medication with a longer duration of action. Indapamide and metolazone are also diuretics that can be used as alternatives to hydroflumethiazide. However, it is important to consult with a healthcare provider before switching or starting any new medication.