Indisposition is a word that is commonly used to refer to a feeling of discomfort or illness, particularly when one is unable to perform their regular activities. However, there are a number of synonyms for this term that can be used to convey a similar meaning. Some of these synonyms include: malaise, unease, discomfort, ailment, affliction, disorder, sickness, weakness, and infirmity. Each of these terms speaks to a feeling of physical or mental discomfort, and can be used in a variety of contexts to describe someone who is not feeling well or is experiencing some form of illness or ailment. Whether used in conversation or in written text, these synonyms can help to add nuance and complexity to our descriptions of illness and discomfort.