Inter-connect refers to a relationship where two or more things are linked or joined together to form a coherent whole. The antonyms for inter-connect would be words that represent the opposite of this relationship. Words such as "disconnect," "separate," "untangle," "disentangle," and "unhook" are all antonyms that describe a situation where things are not linked or associated. Other antonyms include "loosen," "unfasten," "disengage," and "detach." These words convey a sense of isolation or independence, which is the opposite of inter-connect. While inter-connecting can be a positive thing, allowing for greater cooperation and synthesis, it is also important to recognize the value of unconnected and independent entities in certain situations.