When we say "it's someone's loss," we imply that someone missed out on something valuable or important. There are many synonyms for this phrase that express similar sentiments. For example, we can say that someone has "missed out," "lost out," or "failed to take advantage of" something. Another way to phrase this sentiment is to say that someone "let an opportunity slip through their fingers," "passed up a golden opportunity," or "let a chance go to waste." All of these phrases communicate the idea that someone has missed out on something important, and they can be used in a variety of contexts, from personal relationships to business transactions.