The word "lamebrained" is often used to describe someone who is foolish or lacks intelligence. Antonyms for this word would be "smart," "intelligent," "clever," "wise," "astute," "knowledgeable," or "intelligent." These words describe people who are mentally sharp and possess a great deal of common sense. Someone who is smart and knowledgeable is likely to make good decisions based on their understanding of a situation, while someone who is lamebrained may struggle to make sense of things. The antonyms for "lamebrained" are words that describe the opposite of foolishness and incompetence, and instead, evoke an image of mental prowess and sharpness.