Lead off is a phrasal verb that refers to the act of beginning or initiating something. Generally, it is used in the context of sports, where a player or a team member starts a game or an inning. The antonyms of lead off are words that convey the opposite meaning of starting, such as follow up, end, conclude, finish, close, cease, terminate, complete, wrap up, and wind up. These words signify the end of an activity, rather than its beginning. Therefore, when you want to express the idea of an activity's termination, you can use any antonym of lead off that fits the context of your writing or speech.