There are several synonyms for the phrase "loses one's wits," which means to become irrational or mentally unstable. Some common alternatives include "goes crazy," "loses one's mind," "becomes unhinged," "goes off the deep end," and "loses it." Each of these phrases conveys a sense of a person losing control of their emotions or thoughts, and can be used to describe a variety of situations. While losing one's wits may be a troubling experience, it is important to remember that there are resources available to those who may be struggling with mental health issues, and seeking help is a sign of strength, not weakness.
