When a situation or project seems to have no chance of success, it is often called a "lost cause". However, there are several other synonyms that can be used to describe such a situation. Some examples include "hopeless endeavor", "futile attempt", "fruitless pursuit", "unrealistic goal", and "pointless endeavor". Each of these phrases carries a similar meaning to "lost cause" and can be used interchangeably when referring to a situation that appears to have little chance of success. While these phrases may carry a negative connotation, it is important to remember that some endeavors are simply not worth pursuing, and it is better to cut your losses and move on to new opportunities.