Lupus erythematosus is a chronic autoimmune disease that affects various body parts, including skin, joints, and internal organs. Some synonyms for this disease include SLE (systemic lupus erythematosus), discoid lupus erythematosus, cutaneous lupus erythematosus, and subacute cutaneous lupus erythematosus. SLE refers to the most common form of lupus that affects various organs, while discoid lupus erythematosus mainly affects the skin. Cutaneous lupus erythematosus is a term used to describe any form that affects the skin, while subacute cutaneous lupus erythematosus presents a milder form of skin involvement. Other terminologies used for lupus erythematosus include lupus, LE, and chronic cutaneous lupus erythematosus. Understanding the various synonyms for this disease enhances effective communication among healthcare providers and patients.