Lymphogranuloma venereum (LGV) is a sexually transmitted infection caused by certain strains of Chlamydia trachomatis bacteria. Some synonyms for LGV include venereal ulcer of Nicholas-Favre, Durand-Nicolas-Favre disease, Nicolas-Favre-Durand disease, and lymphogranulomatous venereal disease. The symptoms of LGV may include a small, painless sore at the site of infection, swelling of lymph nodes in the genital area, and rectal pain or discharge. LGV can be easily treated with antibiotics, but if left untreated, it can lead to serious complications such as permanent damage to the lymphatic system and chronic pain. Practicing safe sex by using condoms can help prevent the transmission of LGV and other sexually transmitted infections.