"Make a muck of" is a phrase that is commonly used to refer to a situation where one has completely messed up or botched something up. There are several other synonyms that can be used in place of this phrase, including "make a mess of," "screw up," "bungled," "fouled up," "spoiled," and "ruined." All these synonyms share a common theme; they describe an action that has gone terribly wrong. It's essential to be mindful of the words you use when describing a situation to prevent any unintended offence or misunderstanding. When used in the right context, these synonyms are great ways to express a situation where someone has made a significant mistake.