"Mal de la rosa" is a Spanish term that refers to a sexually transmitted disease named syphilis. The term "syphilis" originates from the Greek word "syphilis" which means "swineherd." There are various synonyms for this disease including "great pox," "lues," "French disease," "pox," and "treponema pallidum." Pox is a term that is used to indicate a skin disease that causes small bumps or blisters to appear on the skin. Lues is a Latin term that means "plague," and it was used to refer to syphilis due to the epidemic nature of the disease. In summary, the synonyms for "mal de la rosa" indicate the severe and infectious nature of the disease and are commonly used in medical literature to describe syphilis.