Meclizine is a medication used to treat motion sickness and vertigo. It is also known by several synonyms, including meclozine, meclozine hydrochloride, and dimenhydrinate. Meclizine is a first-generation antihistamine, which means it works by blocking the effects of histamine in the body, reducing the symptoms of motion sickness and vertigo. Other medications that are similar to meclizine include cinnarizine, betahistine, and promethazine. These medications also work by reducing the effects of histamine and can be used to treat similar conditions. When experiencing symptoms of motion sickness or vertigo, it is important to speak with a healthcare professional to discuss the best treatment options.