Meddlesome is a term used to describe someone who interferes in the matters of others without permission or invitation. Synonyms for meddlesome include intrusive, nosy, meddling, interfering, prying, officious, busybody, obtrusive, impertinent, meditative, and nosy-parker. All of these synonyms share the same negative connotation and suggest a lack of respect for personal boundaries or privacy. They are often used to describe a person who is overly curious, controlling, or manipulative. It is important to remember that while it is natural to want to help others, it is essential to know when to step back and respect their autonomy.