Messrs is an abbreviation commonly used to refer to two or more individuals with the same surname, oftentimes in a formal setting. However, there are several synonyms for messrs that can be used interchangeably, including gentlemen, sirs, buddies, pals, mates, and colleagues. Each of these synonyms can be used in place of messrs depending on the context of the conversation or setting. For instance, the word pals can be used when referring to a group of friends, while colleagues may be used when addressing co-workers in a professional setting. Regardless of the context, the use of appropriate synonyms for messrs can help individuals communicate more effectively and respectfully.