Antonyms for the word "most affirmed" include "least validated," "not confirmed," "uncertain," "uncorroborated," "unproven," "doubtful," "controverted," "disproven," "challenged," "refuted," "disputed," and "debated." These words indicate a lack of agreement, reliability or credibility in whatever claim, statement or fact is being discussed. While "most affirmed" implies a high degree of certainty, confidence and agreement, these antonyms suggest skepticism, ambiguity, and a need for further investigation or proof. It is important to consider these opposing ideas when discussing any contentious issue or situation.