Antonyms for the word "most anguished" could include: content, joyful, delighted, pleased, satisfied, peaceful, calm, serene, untroubled, and happy. These words represent the complete opposite of feeling distressed, tormented, and deeply troubled. They capture an image of tranquility, fulfillment, and ease. When we are not anguished, we can find a sense of satisfaction and pleasure in our lives. We can experience joy and happiness without any hindrances. The antonyms for "most anguished" remind us that even in the midst of negativity, there is always a chance for positivity to shine through.