The word "most annoy" is a common phrase used to describe the feeling of being irritated or bothered by something or someone. However, there are several synonyms that can be used instead of "most annoy" to convey the same meaning. These include "exasperate," "aggravate," "vex," "irk," "irked," "frustrate," "exasperated," "annoy," "annoyance," "irritate," "irritated," and "bother." Each of these synonyms provides a different level of intensity or nuance to the feeling of being annoyed. By using these variations, writers can vary their language and better communicate the degree of annoyance they are experiencing.