The word "most bedeviled" refers to a state where someone or something is severely troubled or harassed. The opposite of this would be "least troubled" or "calm." Antonyms for "most bedeviled" could include "peaceful," "tranquil," "serene," "composed," "relaxed," or "untroubled." These words suggest a sense of calmness and tranquility. Examples of their usage in sentences could be, "She sat in her garden, feeling peaceful and calm," or "After a long day at work, he sought out a tranquil spot to unwind." Using antonyms can help convey a sense of serenity and calmness in writing.