Most buzzed refers to a topic, person, or thing that is generating the most excitement or attention. The antonyms for this phrase would be less popular, less talked about, less noteworthy, less significant, less fashionable, less trendy or less hyped. In other words, these are topics or things that do not elicit as much interest or discussion as the ones that are most buzzed. It is important to note that an antonym of "most buzzed" does not mean that the topic or thing is not interesting or valuable, but rather that it tends to fly under the radar in terms of public attention.