Most compounded is an adjective or a phrase used to describe something that is highly complex or difficult to understand due to its many components or factors. Its antonyms would be words or phrases that suggest simplicity, clarity, or straightforwardness. Some possible antonyms for most compounded include simple, uncomplicated, easy, plain, basic, clear, and straightforward. Other antonyms might include single, uncompounded, undivided, or uniform. Depending on the context in which the phrase "most compounded" appears, different antonyms may be more suitable than others. Ultimately, though, the opposite of most compounded is something that is easy to grasp and straightforward.