The term "most comprehending" means having a deep understanding or grasp of something, but there are several antonyms to it. The opposite of comprehending is "ignorant," which means lacking knowledge or awareness. "Uninformed" is another antonym that refers to a person who lacks knowledge or understanding of a particular subject. "Incomprehensible" is another antonym that describes something that is impossible to understand or grasp. Another antonym for "most comprehending" is "unperceptive," which means lacking insight, understanding, or awareness. "Misunderstanding" is another antonym that refers to a failure to grasp or interpret something accurately. In summary, the antonyms for "most comprehending" are ignorant, uninformed, incomprehensible, unperceptive, and misunderstanding.