The phrase "most downside up" implies a situation where things are flipped or turned upside down. Synonyms for this often-used phrase can include "completely topsy-turvy," "utterly inverted," "entirely reversed," or simply "upside down." Each of these words has its own connotations and shades of meaning, but all convey a sense of disorder or disruption. The phrase "most downside up" can be used in a variety of contexts, from describing a chaotic situation to expressing disbelief at an unexpected turn of events. Whatever the situation, these synonyms help convey the sense of unpredictability and disorientation that can arise when things are turned upside down.