The antonyms for the term 'most downside-up' are 'right side up,' 'upright,' 'straight up,' 'erect,' and 'up.' These words are used to describe anything that is in the correct or expected position. In contrast, 'most downside-up' represents anything that is completely opposite of what is normal, predictable, or anticipated. When something is 'right side up,' it is in its natural state, and it is not unusual or unexpected. On the other hand, when something is 'most downside-up,' it is entirely the opposite of what we expect or is usual, and it may seem odd or disturbing.