The antonyms for the word "most high-power" can be "least powerful," "lowly," or "weak." These words denote a lack of strength, influence, or authority. The opposite of high-power is low-power, which means that something or someone has less capability or capacity to achieve their goals. In a corporate or political environment, the most high-power individuals are the executives, politicians, or decision-makers who hold the most significant influence and authority. Conversely, those who are least powerful are often at the bottom of the hierarchy, such as administrative assistants, junior employees, or interns, who must work their way up to gain more power and influence.