The antonyms of "most home free" are "in danger," "at risk," "in trouble," "vulnerable," and "exposed." These words represent the opposite of safety and security, conveying a sense of fear, uncertainty, and instability. Being "in danger" implies that there is a threat that might harm you, while being "at risk" means that you are exposed to potential harm that might occur in the future. "In trouble" suggests that you have already encountered some difficulty, while "vulnerable" refers to your susceptibility to harm due to factors such as age, illness or disability. "Exposed" indicates that you are open to danger, attack, or criticism without any protection.